Angiotensin-Converting Enzyme 2 Activation Improves Endothelial Function

Angiotensin-converting enzyme 2 activation improves endothelial function.

Diminished release and function of endothelium-derived nitric oxide coupled with increases in reactive oxygen species production is critical in endothelial dysfunction. Recent evidences have shown that activation of the protective axis of the renin-angiotensin system composed by angiotensin-converting enzyme 2, angiotensin-(1-7), and Mas receptor promotes many beneficial vascular effects. This ...

Angiotensin Converting Enzyme in Sarcoidosis

Angiotensin-converting enzyme inhibition improves cardiac function. Role of bradykinin.

The effect of chronic low- and high-dose treatment with the angiotensin-converting enzyme (ACE) inhibitor ramipril (0.01 and 1 mg/kg per day) on the development of hypertension and left ventricular hypertrophy as well as on functional and biochemical alterations of the heart was studied in stroke-prone spontaneously hypertensive rats treated prenatally and subsequently up to the age of 20 weeks...

Angiotensin-converting enzyme inhibition improves vascular function in rheumatoid arthritis.

BACKGROUND The excess in cardiovascular risk in patients with rheumatoid arthritis provides a strong rationale for early therapeutical interventions. In view of the similarities between atherosclerosis and rheumatoid arthritis and the proven benefit of angiotensin-converting enzyme inhibitors in atherosclerotic vascular disease, it was the aim of the present study to delineate the impact of ram...

Angiotensin-Converting Enzyme Inhibition Improves Vascular Function in Rheumatoid

Neidhart, Peter Künzler, Frank Enseleit, Daniel Périat, Matthias Hermann, Juerg Nussberger, Andreas J. Flammer, Isabella Sudano, Frank Hermann, Steffen Gay, Adrian Forster, Michel Arthritis Angiotensin-Converting Enzyme Inhibition Improves Vascular Function in Rheumatoid Print ISSN: 0009-7322. Online ISSN: 1524-4539 Copyright © 2008 American Heart Association, Inc. All rights reserved. is publi...